I keep my FsN sighted in for 7 yards using ProtecTOR rounds – I figure that is probably the farthest distance one would realistically use a weapon in a SD situation. I typically practice far more with SS197 though because of the cost factor, although I always put some ProtecTORs through her every time I shoot as well. I rarely shoot paper because I prefer steel plates and the instant feedback you get at each hit.
I finally realized that I didn’t really know the difference in POA/POI for the different rounds because I shoot plates all the time and figured that this is probably good information to know.
So I went to the range with some paper and I shot 3 rounds each of ProtecTOR, S5 and SS197 at seven yards while standing. Point of aim was 1/2” above the black dot (because there is no way to distinguish the holes if I hit the shoot-n-see dot). Here was the result:

Then I tried it again at 15 yards leaving the sights set for 7 yards, this time on a bench & using a sandbag. Same POA (1/2” above the dot). I did have one flier due to an ugly wasp-like insect landing on me as I was squeezing the trigger (wasted an S5 round, grrr). Here’s the result:

I repeated the exercise again and got virtually identical results. So it would seem that within 15 yards the difference in POA/POI between ProtecTORs/S5s is negligible and when using SS197 the difference is within reason. If I was going to use SS197s at 15+ yards out, the sights definitely need to be adjusted.
My real take-away from this exercise though, is that I am apparently a real girly-man, and all a bad guy has to do to get the drop on me is… bring along a trained wasp!
I’m just wondering if anyone else has tried this exercise, and if so, were the results similar?